Publications

2017

33. Lei Wang, Xin Li, Tianyu Sun, Yung-Hao Tsou, Hong Chen, Xiaoyang Xu. “Dual-functional dextran-PEG hydrogel as an antimicrobial biomedical material” Macromol. Biosci. 2017. download32.pdf

32. Lei Wang, Benjamin Griffel, Xiaoyang Xu. “Synthesis of PLGA/lipid hybrid nanoparticles for siRNA delivery using emulsion method” on Methods in molecular Biology. 2017. 

31. Yung-Hao Tsou, He Zhu, Sahla Syed, Xueqing Zhang and Xiaoyang Xu. "Drug delivery to the brain across the blood-brain barrier using nanomaterials". Small. 2017. download31.pdf

 

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2016

30. William Ho, Xue-Qing Zhang, and Xiaoyang Xu. "Biomaterials in siRNA Delivery: A Comprehensive Review" Adv. Healthcare Mater. 2016. download30.pdf​ 

29. Xun Gao, PhDa,1, Yung-Hao Tsou, PhDb,1, Marina Garisb, Haidong Huang, PhDa,⁎, Xiaoyang Xu, PhDb,⁎Highly specific colorimetric detection of DNA oxidation biomarker using gold nanoparticle/triplex DNA conjugate. Nanomedicine: Nanotechnology, Biology and Medicine. 2016; (1 contribute equally)Download29.pdf

28. Yung-Hao Tsou, Joe Khoneisser, Ping-Chun Huang, Prof. Dr. Xiaoyang Xu. "Hydrogel as a bioactive material to regulate stem cell fate" Bioactive Materials. 2016; 1-17.Download28.pdf

              

27. Yuan Xue,1 Xiaoyang Xu, 1 Xueqing Zhang, Omid C Farokhzad, Robert S Langer. “Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles with drug delivery amplification” Proc Natl Acad Sci USA. 2016; (1 contribute equally) Download27.pdf

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2015

26. Xi Zhu, Yingjie Xu, Luisa M Solis, Wei Tao, Liangzhe Wang, Carmen Behrens, Lili Zhao,  Xiaoyang Xu, Danyl Liu, Jun Wu, Ning Zhang, Ignacio I Wistuba, Omid Farokhzad, Bruce R Zetter, Jinjun shi*. “Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment” Proc Natl Acad Sci USA. 2015; 112(25), 7779-84. Download26.pdf

25. Xiaoyang Xu*, William Ho, Xueqing Zhang, Nicolas Bertrand, and Omid Farokhzad*. “Cancer nanomedicine: from targeted delivery to combination therapy” Trends in molecular Medicine. 2015; 21, 233-244. Download25.pdf

24. Haisheng Peng, Chao Wang, Xiaoyang Xu, Chenxu Yu, and Qun Wang*. “An Intestinal Trojan Horse for Gene Delivery” Nanoscale 2015; 7, 4354-4360. Download24.pdf

23. Zhang, X.; Even-Or, O.; Xu, X.; Rosmalen, M.; Lim, L.; Gadde, S.; Farokhzad, O.; Fisher, E. A. “Nanoparticles Containing a Liver X Receptor Agonist Inhibit Inflammation and Atherosclerosis” Adv. Healthcare Mater. 2015; 4(2):228-236. Download23.pdf

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2014

22. Wu, J.; Kamly, N.; Shi, J.; Zhao, L.; Xiao, Z.; Hollett, G.; John, R.; Ray. S.; Xu, X.; Zhang, X; Kantoff, P.; Farokhzad C. O. “Development of multinuclear polymeric nanoparticles as robust protein nanocarriers” Angew. Chem. Int. Ed. 2014 Download.pdf

21. Shi, J.; Xu, Y.; Xu, X.; Zhu, X.; Pridgen, E.; Votruba, A.; Zetter, B.; Farokhzad C. O. “Hybrid Lipid-Polymer Nanoparticles for Sustained siRNA Delivery and Gene Silencing” Nanomed Nanotech Biol Med 2014 Download.pdf

20. Bertrand, N.; Wu, J.; Xu, X.; Kamaly, N.; Farokhzad, C. O. “Cancer Nanotechnology: The impact of passive and active targeting in the era of modern cancer biology” Adv. Drug Deliv. Rev. 2014; 66, 2-25.Download.pdf

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19. Xu, X; Xie, K; Zhang, X; Pridgen, E; Park, G; Lippard, S. J.; Langer, R. S.; Walker G. C.; Farokhzad C. O. “Enhancing Tumor Cell Response to Chemotherapy through Nanoparticle-Mediated Co-delivery of siRNA and Cisplatin Prodrug” Proc Natl Acad Sci USA. 2013; 110(46), 18638-18643.Download.pdf

18. Xu, X*; Zhang, X*; Bertrand, N; Pridgen, E; Swami A; Farokhzad C. O. “Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine” Adv. Drug Deliv. Rev.; 2012; 64(13), 1363-1384. (* equally contribute)Download.pdf

17. Cheng H; Byrska-Bishop M; Zhang T. C; Kastrup J. C; Hwang S. N; Tai K. A; Lee W. W; Xu X; Nahrendorf M; Langer S. R; Anderson G. D. “Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell–selectin interaction kinetics” Biomaterials; 2012; 33(20), 5004-5012.Download.pdf

16. Xu, X.; * Zhang, X.;* Lam, R.; Giljohann, D.; Ho, D.; and Mirkin C. A. “A Strategy for Increasing Drug Solubility and Efficacy through Covalent Attachment to Polycalent DNA-Nanoparticle Conjugates.” ACS Nano, 2011, 5 (9), 6962–6970. (* equally contribute) (9.855)Download.pdf

15. Zhang, X.; Lam, R.; Xu, X.; Kim, H.; and Ho. D. “Multimodal Nanodiamond Drug Delivery Carriers for Selective Targeting, Imaging and Enhanced Chemotherapeutic Efficacy” Adv. Mater. 2011; 23(41), 4770-4775.Download.pdf

14. Cutler, J. I.; Zheng, D.; Xu, X.; Jiyohann D. A.; Mirkin C. A. "Polyvalent Oligonucleotide Iron Oxide Nanoparticle "Click" Conjugates" Nano Lett.; 2010; 10 (4), 1477–1480.Download.pdf

13. Shimkunas, R; Robinson, E; Lam, R; Zhang, X; Xu, X; Ho, D. “Nanodiamond-Insulin Complexes as pH- Dependent Protein Delivery Vehicles.” Biomaterials. 2009; 30 (29), 5720-5728.Download.pdf

12. Xu, X.; Deniel, W.; Wei, W.; Mirkin, C. A. "Colorimetric Detection Cu2+ using DNA/Nanoparticle Conjugates and Click Chemistry " Small; 2009; 6 (5), 623-626 (7.333).Download12.pdf

11. Zhang, X; Chen, M; Lam, R; Xu, X; Ho, D; “Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery.” Acs Nano. 2009; 3(9), 2609-2616.Download.pdf

10. Xu, X.;* Song, Y.;* MacRenaris, K. W.; Zhang, X.; Mirkin, C. A.; Meade, T. J. " Multimodal Gadolinium-Enriched DNA Gold Nanoparticle Conjugates for Cellular Imaging" Angew. Chem. Int. Ed. 2009; 48(48), 9143-9147. (* equally contribute) (12.186)Download.pdf

9. Wei, W; Li, S; Millstone, J. E; Banholzer, M; Chen, X; Xu, X; Schatz, G. C.; Mirkin, C. A. "Surprisingly Long-Range Surface Enhanced Raman Scattering (SERS) on Au-Ni Multisegmented Nanowires" Angew. Chem. Int. Ed. 2009; 48, 4210-4212.Download.pdf

8. Zhang, X; Tang, H; Hosh, I; Laporte, L. D; Qiu, H; Xu, X; Shea, L. D.; Ameer, G. A."Sustained Transgene Expression via Citric Acid-based Polyester Elastomers" Biomaterials. 2009; 30(13), 2632- 2641.Download.pdf

7. Xu, X.; Zhao, Z.; Qin, L.; Wei, W.; Levin, J. E.; Mirkin, C. A. "A Fluorescence Recovery Assay for the Detection of Protein-DNA binding" Anal.Chem. 2008; 80(14); 5616-5621.(5.874)Download.pdf

6. Wei, W., Qin, L.; Xue, C.; Millstone, J. E.; Xu, X.; Li, S.; Schatz, G. C.; Mirkin, C. A."Surface Plasmon-Mediated Energy Transfer in Heterogap Au−Ag Nanowires" Nano Lett.; 2008; 8 (10), 3446–3449.Download.pdf

5. Millstone, J. E.; Georganopoulou, D. G.; Xu, X.; Payne. E. K.; Mirkin, C. A. "DNA-Gold Triangular Nanoprism Conjugates" Small; 2008; 4(12), 2176- 2180.Download.pdf

4. Xu, X.; Georganopoulou, D. G.; Hill, H. D.; Mirkin, C. A. "Homogeneous Detection of Nucleic Acids Based Upon the Light Scattering Properties of Silver-coated Nanoparticle Probes" Anal. Chem. 2007; 79(17); 6650-6654. (5.874)Download.pdf

3. Qin, L.; Banholzer, M. J.; Xu, X.; Huang, L.; Mirkin, C. A. "Rational Design and Synthesis of Catalytically Driven Nano Rotors " J. Am. Chem. Soc. 2007; 129(48); 14870-14871Download.pdf

2. Xu, X.; Han, M. S.; Mirkin, C. A. "A Gold-Nanoparticle-Based Real-Time Colorimetric Screening Method for Endonuclease Activity and Inhibition" Angew. Chem. Int. Ed. 2007; 46(19); 3468-3470. (Selected as "VIP paper") (12.186)Download.pdf

1. Xu, X.; Rosi, N. L.; Wang, Y.; Huo, F.; Mirkin, C. A. "Asymmetric Functionalization of Gold Nanoparticles with Oligonucleotides " J. Am. Chem. Soc. 2006; 128(29); 9286- 9287.( Highlighted by Nature Nanotechnology, 14 July 2006) (Impact factor: 9.019)Download.pdf