ICP-MS

  • Agilent 7900 ICP-MS system: Coming soon (ordered) !!!

  • Agilent 7500i Benchtop Inductively Coupled Plasma-Mass Spectrometer System - ICP-MS


EPA methods:

Method 6020 : Inductively Coupled - Mass Spectrometry;
Method 200.8: Determination of trace elements in waters and wastes by Inductively Coupled - Mass Spectrometry.


In addition to a traditional quantitative analysis, the ICP-MS allows to perform fast semi-quantitative analysis of unknown samples, when an external calibration is not required (it is accurate to +/-30% or better on completely unknown samples).

All above-listed instruments serve the same purpose: to perform metals analysis on solution. They can be used for the determination of metals in a wide variety of sample types (drinking water, groundwater, other aqueous samples, industrial wastes, soils, sludge, sediments, and other solid samples) in different application areas such as Environmental, Chemicals/Petrochemicals, Pharmaceutical, Semiconductor Manufacturing, Metallurgy, etc. However, there is no universal single technique, which will suit all of analytical needs. Your choice of technique/instrument should be based on the criteria summarized in the following table.

 

 

AAS

GFAAS

ICP-MS

Detection Limit

 

 

Very good for some elements
(in the sub-ppm range)

Excellent for some elements
(in the sub-ppb range)
 

Excellent for most elements
(typically, 1-10 ppt)

Speed/Sample Throughput

 

Fast
(10-15 secs per element)

Slow
(3-4 mins per element)

Fast
(All elements in <1 min)

Dynamic Range

103

102

109

Interferences:

Spectral

Chemical (matrix)

Physical (matrix)

 

Very few
Many
Some

 

Very few
Many
Very few

 

Few
Some
Some

Multi-Element

No

No

Yes

Elements Applicable to

68+

50+

82 (all metals from lithium to uranium)

Sample Volumes Required

Large (ml)

Very small (μl)

Very small (μl or ml)

Semiquantitative Analysis

No

No

Yes

Isotopic Analysis

No

No

Yes

Ease to Use

Very easy

Moderately easy

Moderately easy

Method Development

Easy

Difficult

Difficult

Running Costs

Low

Medium

High